Sunway Biofunctional Molecules Discovery Centre

Overview

Fundamental and application-driven discoveries through the cutting-edge facilities available at the Research Centre, the Sunway Biofunctional Molecules Discovery Centre (SBMDC) fosters interdisciplinary collaboration by strategically aligning its research focus with the priorities of the Faculty of Medical and Life Sciences and the broader objectives of the University.

Vision

To be a globally recognized leader in biofunctional molecules research and innovation to create positive impact on human health, environmental and sustainable development. 

Mission

To conduct world-class research in the development and characterization of novel biofunctional molecules that brings value and benefit to industry and society.

Research Areas

  1. Drug discovery
  2. Metal-organic frameworks
  3. Cancer biology
  4. Molecular oncology
  5. In silico modeling and quantum chemistry
  6. Single cell technology and applications
  7. Multi-omics
  8. Neuroscience
  9. Bioprospecting 

Research Facilities and Services

The laboratory houses several state-of-the-art research instruments with majority of them equipped with temperature modulator suitable for quantitative and qualitative analysis of chemical and biological samples.
LECO TruSpec Micro CHNS Elemental Analyser

Capable for the determination of C, H, N and S elements 

 

Bruker Vertex 70v FT-IR Spectrometer 
  1. Platinum-ATR-accessory
  2. Measurement range (in vacuum condition): 80 to 4000 cm-1

 

Shimadzu UV3600 Plus UV/Vis/NIR Spectrophotometer 
  1. Wavelength range: 200 to 1010 nm
  2. Temperature range: 10°C to 90°C (Solution)
  3. Solid state attachment

 

Leica DM2700P Optical Polarizing Microscope
  1. With Linkam LTS420 Heating and Cooling Stage
  2. Temperature range: -196 to 420°C
  3. PointGrey Grasshopper 5 MP Color Digital Camera 

 

Perkin Elmer DSC8000 Differential Scanning Calorimeter 
  1. Liquid nitrogen cooling system
  2. Temperature range: -170 to 200 °C

 

Perkin Elmer STA6000 Thermogravimetric  Analyzer 
  1. Simultaneous analysis of TG with DTA and DSC (mW) modes
  2. Temperature range: 25 to 900 °C 

 

Jasco FP-8600 Photoluminescence Spectrometer 
  1. Wavelength range: 200 to 1010 nm
  2. Temperature range: 10°C to 90°C (Solution)
  3. OptistatDN2 (Solid State Analysis)
  4. Temperature range: -170°C to 25°C 

 

Micromeritics 3Flex 3500 BET Surface Area Analyzer
  1. SmartVacPrep
  2. Cryostat (25 to 300K) 

 

Retsch Cryomill
  1. Frequency: 5 - 30 Hz (300 - 1800 min-1)
  2. Grinding jar: adapter for 6 x 2 ml tubes and 5 ml stainless steel jar
  3. Operating temperature: ambient RT or -196°C 

 

Anton Paar Monowave 450 Microwave Synthesizer
  1. Max power: 850 W
  2. Max. IR temperature: 300 °C
  3. Max. operation pressure 30 bar
  4. With integrated camera and auto-sampler 

 

Bruker Avance III HD400 MHz Nuclear Magnetic Resonance Spectrometer 
  1. Nuclei ranging from 15N to 31P and 19F with 1H decoupling
  2. Temperature range: -150 to 150°C.
  3. Equipped with Magic Angle Spinning (MAS) probes for solid samples 

 

Rigaku XtaLAB Synergy-S Single Crystal X-Ray Diffractometer 

High intensity dual microfocus PhotonJet-S X-ray sources (Mo/Cu wavelength) 

 

Rigaku SmartLab 3kW Powder X-Ray Diffractometer 
  1. Anton Paar TTK 600 low temperature attachment
  2. Temperature range: -190 to 600°C (vacuum) 

 

Rigaku Miniflex 600 benchtop Powder X-Ray Diffractometer 
  1. Room temperature measurement
  2. Rapid analysis 

 

Class II Biological Safety Cabinet (FMLS Facilities)

For cell culture work 

 

CO₂ Incubator (FMLS Facilities)

Provide optimal growing conditions for cell cultures

 

LMO / GMO Freezer  (FMLS Facilities)
  1. Temperature : -80°C
  2. For the storage of LMO / GMO samples 

 

Cryogenic Storage System (FMLS Facilities)
  1. Temperature : -196°C to -210°C
  2. Long term storage of biological samples

 

Fluorescence Microscope (FMLS Facilities)
  1. Nikon Eclipse Ti
  2. 4 - colours imaging

 

HPLC (FMLS Facilities)

Agilent 1200 Infinity Series

 

BD FACSCelesta™ Flow Cytometer (SUMC Facilities)
  1. Multiple fluorochrome system
  2. For cell analysis, assay development, verification, and identification of cellular populations of interest

 

Dolomite Fluidics Equipment (SUMC Facilities)

Used for a wide range of applications, including drug encapsulation, droplet manufacture and nanoparticle generation

 

Real-Time PCR Cycler (DMS Facilities)
  1. QIAGEN's Rotor-Gene Q
  2. Centrifugal rotary design

 

cellenONE® X1 Neo

cellenONE® is an all-in-one platform combining high-accuracy single cell isolation and high-precision pico to nanoliter reagent dispensing.

  1. Image-based single-cell sorting and isolation
  2. Cell line development with excellent clonal outgrowth
  3. Miniaturized end-to-end single-cell sample preparation workflows