Dr Eden Low Ngah Den

Dr Eden Low Ngah Den

  • Lecturer
Department of Biomedical Sciences
  • Jeffrey Cheah Sunway Medical School
Faculty of Medical and Life Sciences
SDGs Focus
Good Health and Well Being
Quality Education
Reduced Inequalities
Life On Land

Biography

Dr Eden Low is a Lecturer in the Department of Biomedical Sciences at Sunway University. She obtained her PhD in Medical Science (Physiology) from Universiti Kebangsaan Malaysia in 2021 and holds a BSc in Molecular Genetics from The Ohio State University, USA. Her academic and research journey reflects a consistent focus on bridging molecular mechanisms with clinical applications, particularly in gastrointestinal and metabolic diseases.

Prior to joining Sunway University, Dr Eden Low worked as a postdoctoral associate at the Center of Pharmacogenetics, University of Pittsburgh, where she worked on knockout mouse models to investigate the mechanisms underlying liver fibrosis. During her doctoral training, she gained extensive experience in both fundamental and clinical research, contributing to multiple projects on inflammatory bowel disease (IBD), colitis-associated colorectal cancer, and metabolic liver diseases (NAFLD/MAFLD). She is currently working on projects related to healthy ageing and saliva microbiome.

Academic & Professional Qualifications

  • PhD in Medical Science (Physiology), Universiti Kebangsaan Malaysia, Malaysia (2021)
  • BSc in Molecular Genetics, The Ohio State University, USA (2013)

Research Interests

  • Inflammatory bowel disease
  • Colitis-Associated Cancer
  • Liver Diseases
  • Saliva microbiome
  • Healthy Ageing
  • Saliva Biomarkers in Mental Health

Notable Publications

  1. Chia YC, Low EN, Teh JK, Chew J, Thanaraju A, Lim WG, Vafa S, Jenkins MJ. Association between physical activity and cognitive function in a multi-ethnic Asian older adult population. Scientific Reports. 2025 Feb 28;15(1):7249. https://doi.org/10.1038/s41598-025-92074-w

  2. Mokhtar NM, Nawawi KN, Verasingam J, Zhiqin W, Sagap I, Azman ZA, Mazlan L, Hamid HA, Yaacob NY, Rose IM, Den EL. A four-decade analysis of the incidence trends, sociodemographic and clinical characteristics of inflammatory bowel disease patients at single tertiary centre, Kuala Lumpur, Malaysia. BMC Public Health. 2019 Jun;19:1-0. https://doi.org/10.1186/s12889-019-6858-2

  3. Low EN, Mokhtar NM, Wong Z, Raja Ali RA. Colonic mucosal transcriptomic changes in patients with long-duration ulcerative colitis revealed colitis-associated cancer pathways. Journal of Crohn's and Colitis. 2019 May 27;13(6):755-63.  https://doi.org/10.1093/ecco-jcc/jjz002

  4. Mokhtar, Norfilza, Den Low, Eden Ngah, Azyani Yahaya, and Raja Affendi Raja Ali. "Characterisation of SGK2 gene using CRISPR/Cas9 gene editing tool in ulcerative colitis." In Journal Of Gastroenterology And Hepatology, vol. 34, pp. 274-274. 111 River St, HOBOKEN 07030-5774, NJ USA: WILEY, 2019. PP0401 https://onlinelibrary.wiley.com/doi/full/10.1111/jgh.14879?af=R

  5. Chan SN, Den Low EN, Ali RA, Mokhtar NM. Delineating inflammatory bowel disease through transcriptomic studies: current review of progress and evidence. Intestinal research. 2018 Jul;16(3):374.  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077315/

  6. Ali, Raja Affendi Raja, Eden Ngah Den Low, Zhiqin Wong, Chai Soon Ngiu, Seow-Neng Chan, and Norfilza Mohd Mokhtar. "Tu1800-Colonic Mucosal Transcriptomic Changes in Patients with Long Duration Ulcerative Colitis Revealed Colitis-Associated Cancer Pathways." Gastroenterology 154, no. 6 (2018): S-1023.  https://www.gastrojournal.org/article/S0016-5085(18)33426-7/pdf?referrer=https%3A%2F%2Fwww.researchgate.net%2F

  7. Low, E. N. D., Z. Wong, C. S. Ngiu, A. H. Nazefah, A. R. Rafiz, N. Mokhtar, and RA Raja Ali. "P031 Identification of alternative splicing in transcript isoforms in patients with ulcerative colitis: effects of disease duration." Journal of Crohn's and Colitis 11, no. suppl_1 (2017).  https://academic.oup.com/ecco-jcc/article/11/suppl_1/S94/2960975